YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
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In vitro Activities and in vivo Efficacies of DA-074 a New Cephalosporin

새로운 세파로스포린 항생제 DA-074의 in vitro 항균력과 감염치료효과

  • Published : 2000.08.01
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Abstract

The in vitro activities of DA-074, a new cephalosporin against 34 various standard strains and its in vivo efficacies against 6 important strains were obtained. DA-074 showed two fold enhanced in vitro antibacterial activity against some Pseudomonas aeruginosa compared to Ceftazidime and more than 2 fold in vivo efficacy against Staphylococcus aureus Smith, Klebsiella pneumoniae 1 and Escherichia coli KC-14, compared to Cefpirome. DA-074 might be a good candidate for further evaluations.

Keywords

References

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  6. 아졸을 포함하는 신규 세파로스포린 유도체의 합성 및 항균력 임중인;신현태;윤영구;양재성;조종환;윤석균;김원배;장민선;최성학;임원빈;이재걸