Characteristics of Photochemical Reaction of Pefloxacin Irradiated by UVB in an Aerobic Condition

산소 존재하에서 UVB에 의한 페플록사신의 광화학적 반응의 특성

  • 최윤수 (대구효성가톨릭대학교 약학대학) ;
  • 이경선 (영남대학교 약학대학)
  • Published : 2000.02.01

Abstract

The photodegradation of pefloxacin, photolabile fluoroquinolone antibacterial agent, was studied. In the presence of $N_2$, photodegradation of pefloxacin was suppressed. The singlet oxygen and free radical generated in the reaction media proceeded photochemical reaction. The photodegradation of peflxacin was sensitized by benzophenone, a triplet state sensitizer.

Keywords

References

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