Archives of Pharmacal Research
- 제23권5호
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- Pages.438-440
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- 2000
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Total Synthesis of a Demethoxy-egonol from Styrax obassia
- Choi, Hong-Dae (Department of Chemistry, Dongeui University) ;
- Ha, Mun-Choun (Department of Chemistry, Dongeui University) ;
- Seo, Pil-Ja (Department of Chemistry, Dongeui University) ;
- Son, Byeng-Wha (Department of Chemistry, Pukyong National University) ;
- Song, Jin-Cherl (Department of Polymer Science and Engineering, Pusan National University)
- 발행 : 2000.10.01
초록
The total synthesis of a demethoxy-egonol isolated from Styrax obassia, 5-(3-hydroxypropyl)-2-(3',4'-methylenedioxyphenyl)benzofuran (9), is described. The key steps involve the construction of a 2-arylbenzofuran skeleton 7 from methyl 3-(4-hydroxyphenyl)propionate with 2-chloro-2-methylthio-(3',4'-methylenedioxy) acetophenone (6) in the presence of ZnCl
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