Journal of Microbiology and Biotechnology

  • 제10권5호
  • /
  • Pages.733-736
  • /
  • 2000
  • /
  • 1017-7825(pISSN)
  • /
  • 1738-8872(eISSN)
한국미생물·생명공학회 (The Korean Society for Microbiology and Biotechnology)
권호 표지

Comparison of the Solution Structure of Vancomycin with Its X-ray Crystallographic Structure

  • Lee, Chul-Hoon (Department of Medical Genetics, College of Medicine, Hanyang University) ;
  • Kyung, Han-Soo (Department of Medical Genetics, College of Medicine, Hanyang University) ;
  • Lim, Yoong-Ho (Department of Applied Biology & Chemistry, Konkuk University)
  • 발행 : 2000.10.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Since pathogens resistant against vancomycin occur rapidly, the development of a new drug is needed. To make a new drug based on a rational drug design, the structural study of vancomycin is necessary. Accordingly, this study reports on a comparison of the solution structure of vancomycin determined by NMR spectroscopy, which was performed in the present work, with the X-ray crystallographic structure previously deposited in the Protein Data Bank (PDB).

키워드

참고문헌

  1. J. Magn. Reson v.65 MLEV-17-based two-dimensional homonulear magnetization transfer spectroscopy Bax, A.;D. G. Davis
  2. J. Magn. Reson v.43 A simple method for suppressing dispersion-mode contributions in NMR spectra: The "pseudo echo" Bax, A.;R. Freeman
  3. J. Magn. Reson v.55 Correlation of proton and nitrogen-15 chemical shifts by multiple quantum NMR Bax, A.;R. H. Griffey;B. L. Hawkins
  4. J. Magn. Reson v.48 Distoritionless enhancement of NMR singnals by polarization transfer Dodrell. D. M.;D. T. Pegg;M. R. Bendall
  5. Science v.266 Vancomycin resistance: Structure of D-alanine:D-alanine ligase at 2.3A resolution Fan, C.;P. C. Moews;C. T. Walsh;J. R. Knox
  6. Structure(London) v.8 Enzymes of vancomycin resistance: The structure of D-alanine-D-lactate ligase of naturally resistant Leuconostoc mensenteroids Kuzin, A. P.;T. Sun;J. jorczak-Baillass;V. L. healy;C. T. Walsh;J. R. Knox
  7. J. Syst. Bacteriol v.36 Two new genera of nocardioform actinomycetes; Amycolata gen. nov. and Amycopatosis gen. nov Lechevalier, M. D.;H. Prauser;D. P. Labeda;J. S. Ruan
  8. J. Microbiol. biotechnol v.9 Antibacterial activity of antimycotic miconazole against methicillin-resistant Staphylococcus aureus Lee, S.-H.;C.-J. kim
  9. J. Med. Chem. v.42 Vancomycin binding to law affinity ligands: Delineating a minimun set of interactions necessary for high affinity binding Loll, P. J.;J. Kaplan;B. Selinsky;P. H. Axelsen
  10. Am. J. Med. v.94 Methicillin-resistant Staphylococcus aureus: A consensus review of the microbiology,pathogenesis,and epidemiology with implication for prevention and management Mulligan, M. E.;H. C. Standiford
  11. Eur. J. Clin. Microbiol. Infect. Dis v.8 Structure biochemistry and mode of action of glycopeptide antibiotics Reynolds, P. E.
  12. Agri. Chem. Biotechnol v.43 Determination of the substituted position of piperazine in substitution reaction of oxazolidinones Park, J.;J. Suh;J. Kim;C. Kim;K. Kim;Y. Lim
  13. Structure(London) v.4 Crystal structure of vancomycin Schafer, M.;T. R. Schneider;G. M. Sheldrick
  14. J. Magn. Reson v.61 Sensitivity of two-dimensional NMR experiments for studying chemical exchange Turner, D. L.