Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Comparison of the Solution Structure of Vancomycin with Its X-ray Crystallographic Structure

  • Lee, Chul-Hoon (Department of Medical Genetics, College of Medicine, Hanyang University) ;
  • Kyung, Han-Soo (Department of Medical Genetics, College of Medicine, Hanyang University) ;
  • Lim, Yoong-Ho (Department of Applied Biology & Chemistry, Konkuk University)
  • Published : 2000.10.01
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Abstract

Since pathogens resistant against vancomycin occur rapidly, the development of a new drug is needed. To make a new drug based on a rational drug design, the structural study of vancomycin is necessary. Accordingly, this study reports on a comparison of the solution structure of vancomycin determined by NMR spectroscopy, which was performed in the present work, with the X-ray crystallographic structure previously deposited in the Protein Data Bank (PDB).

Keywords

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