한국가금학회지 (Korean Journal of Poultry Science)

  • 제27권2호
  • /
  • Pages.91-98
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  • 2000
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  • 1225-6625(pISSN)
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  • 2287-5387(eISSN)
한국가금학회 (The Korean Society of Poultry Science)
권호 표지

닭 전염성 기관지염 바이러스 한국분리주의 분자생물학적, 역학적 특성

Molecular and Epidemiological Characteristics of Infectious Bronchitis Virus Isolated in Korea

  • 송창선 (국립수의과학검역원 조류질병과) ;
  • 이윤정 (국립수의과학검역원 조류질병과)
  • 발행 : 2000.08.01
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초록

Phylogenetic tree constructed from the nucleotide sequences of the S1 gene showed that the 15 Korean strains of infectious bronchitis virus(IBV) examined were classified into 2 genetically distinct groups, except one respiratory strain, RB86, which was clustered with Massachusetts group. All the 5 respiratory strains belonged to Korean group I and the rest 9 nephropathogenic strains belonged to Korean group II according to the analysis, based on S1 gene sequences. Like previous classifications corresponded with the geographic origin, Korean stains were discriminated from geographically distinct reference strains of IBV. The nephropathogenic strains within Korean group IIsharing 96% homology were continuously isolated since 1990, and seemed to be genetically stable. Whereas the respiratory strains within Korean group Ⅰ sharing 88% homology were sporadically isolate since 1986m and seemed to be genetically unstable. Because we found putative accumulated point mutation as well as recombination events in Korean group Ⅰ, we discussed why genetic variations have often occurred in respiratory strains rather than nephropathognic strains.

키워드

참고문헌

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