Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Efficacy of Terbinafine in Guinea Pigs Experimentally Infected with Microsporum gypseum Isolated from Naturally Infected Dog II. Clinical and Mycological Efficacy

자연감염된 개에서 분리한 Microsporum gypseum을 인공감염시킨 기니픽에서 Terbinafine의 효과 II. 임상적 ald 진균학적 효과

  • 임채형 (서울동물의료원, 서울대학교 수의과대학) ;
  • 이창우 (서울동물의료원, 서울대학교 수의과대학)
  • Published : 2000.06.01
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Abstract

알비노 기니픽의 피부에 Microsporum gypseum을 접종한 후 체중 kg당 20, 40 및 80mg의 terbinafine을 접종 당일부터 9일간 연속 투여하였다. 대조군의 피부는 인설과 가피를 동반한 현저한 염증이 발생되었다. 이와 대조적으로 terbinafine을 경구투여한 처치군에서는 피부 증상이 현저하게 차도를 보였다. 진균학적인 평가를 위해 모근침범시험을 실시 하였다. 체중 kg 당 20∼80mg의 terbinafine을 경구투여한 처치군은 진균학적으로 97∼100%의 치료효과를 나타냈으며, 대주군에서는 치료효과가 전혀 없었다.

Keywords

References

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