Preventive Nutrition and Food Science
- Volume 5 Issue 2
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- Pages.114-118
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- 2000
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- 2287-1098(pISSN)
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- 2287-8602(eISSN)
Inhibitory Effect of Doenjang(fermented Korean soy paste) Extracts and Linoleic Acid on the Growth of Human Cancer Cell Lines
- Park, Kun-Young (Pusan National University) ;
- Lee, Jeong-Min (Pusan National University) ;
- Moon, Suk-Hee (Kyungnam College of Information and Technology) ;
- Jung, Keun-Ok (Pusan National University)
- Published : 2000.06.01
Abstract
The inhibitory effects of doenjang extracts and linoleic acid(LA) which was identified as one of the active compounds in doenjang on the growth of human cancer cells were studied, comparing to the actions on normal cells. Methanol extract and hexane fraction from doenjang exhibited the strong growth inhibitory effect on HT-29 human colon carcinoma cells. Inhibitory effects of chloroform, ethyl acetate, butanol and aqueous fractions on the cancer cells were observed, moderately or weakly. When cell counts of SNU-C