Biotechnology and Bioprocess Engineering:BBE

  • 제5권3호
  • /
  • Pages.169-173
  • /
  • 2000
  • /
  • 1226-8372(pISSN)
  • /
  • 1976-3816(eISSN)
한국생물공학회 (The Korean Society for Biotechnology and Bioengineering)
권호 표지

PCR Analysis of Four Length-Polmorphic Loci in Korea Population for Genotyping

  • Ryu, Jae-Song (Department of Biological Engieering, Inha University, Inchon 402-751) ;
  • Koo, Yoon-Mo (Department of Biological Engieering, Inha University, Inchon 402-751) ;
  • So, Jae-Seong (Department of Biological Engieering, Inha University, Inchon 402-751)
  • 발행 : 2000.06.01
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초록

On human chromoscomes, a short sequence of DNA is known to repeat a number of times. These are called variable number of tandem repeat (VNTR) or short tandem respeat (STR) which has a short core. VNTR and STR are used in the filed of forensic science, evolution, and anthropology. In this work, we examined allele frequencies of one VNTR (YNZ22) and three STRs (NeuR, D21S11, Humth01) in a korean population sample by polymerase chain reaction (RCP) followed by high-resolution polyacrylamide gel electro-phoresis (PAGE) with silver stain. Subsequently, the polymorphism information content (PIC) was calculated : the hifhest PIC was observed in the NeuR locus (0.95680) and lowest in the Humth01 locus (0.75809).

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참고문헌

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