The Journal of Korean Physical Therapy

The Korean Society of Physical Therapy (대한물리치료학회)
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A Study in Heat Shock Protein 70

열충격단백질 70에 대한 연구

  • Nam Ki-Won (Taegu University Rehabilitation Clinic) ;
  • Kim Jin-Sang (Department of Physical Therapy, College of Rehabilitation Science, Taegu University) ;
  • Choi Jin-Ho (Department of Physical Therapy, Yeongdong Junior College)
  • 남기원 (대구대학교 재활의원) ;
  • 김진상 (대구대학교 재활과학대학 물리치료학과) ;
  • 최진호 (영동전문대학 물리치료과)
  • Published : 2000.04.01
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Abstract

Heat shock protein 70(HSP70) is induced by elevated temperature and many other types of stresses in cell. HSP70 ensures cell survival under stressful condition that would lead to irreversible cell damage and ultimately to cell death. HSP70 plays essential role in the synthesis, transport, and folding of proteins and is often refferred to as molecular chaperones. Increased levels of HSPs occur after arthritis, infection, imflammation, autoimmune disease and CNS injury such as infarction, ischemia, seizure and Alzheimer's disease. Also, HSP70 increases resistance to apoptosis. The recent studies that the expression of the HSP has been processed at various field. However, they an still relatively line studied in clinically application. This review summarizes the fundamental knowledge of HSP.

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