대한치과교정학회지 (The korean journal of orthodontics)
- 제30권6호
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- Pages.713-721
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- 2000
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- 2234-7518(pISSN)
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- 2005-372X(eISSN)
쥐의 골세포에서 $PGE_2$ 합성과 plasminogen activator 활성 조절에 의한 IL-$1{\beta}$ 의 골 흡수유도와 TGF-$\beta$ 에 의한 골 흡수 억제 기전에 관한 연구
Interleukin-$1{\beta}$ induces bone resorption by regulation of prostaglandin $E_2$ synthesis and plasminogen activator activity, and TGF-$\beta$ inhibits bone resorption of rat bone cells
- Kim, Young-Hun (Orthodontics, Kyung Hee University) ;
- Lee, Young-Jun (Orthodontics, Kyung Hee University) ;
- Chung, Kyu-Rhim (Orthodontics, Kyung Hee University) ;
- Park, Young-Guk (Orthodontics, Kyung Hee University)
- 발행 : 2000.12.01
초록
골세포는 골대사에 영향을 미치는 다양한 성장인자와 싸이토카인을 생성하여 골 기질로 유리시킨다. 이 연구는 쥐의 장골 세포 배양 모델에서 recombinant human IL-
Bone cells produce multiple growth factors and cytokines that have effects on bone metabolism and can be incorporated into the bone matrix. The present study was designed to extend these observations by examining the interactions between transforming growth factor-