대한방사선치료학회지 (The Journal of Korean Society for Radiation Therapy)
- 제12권1호
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- Pages.166-173
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- 2000
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- 1598-8449(pISSN)
방사선을 조사한 혈관내피세포에 대한 Angiopoietin-1의 방사선 방어 기작
Angiopoietin-1 Is An Radiation-induced Apoptosis Survival Factor for Human Umbilical Vein Endothelial Cells
- Lee, Song-Jae (Dept. of Radiotechnology, Sohae College) ;
- Chang, Chae-Chul (Dept. of Chemistry, Kunsan National University)
- 발행 : 2000.12.01
초록
Angiopoietin-1(Ang-1) is a vasculogenic factor that signals through the endothelial cell-specific Tie2 receptor tyrosine kinase. We examined the effect of angiopoietin-1(Ang-1) on radiation-induced apoptosis in human umbilical vein endothelial cells(HUVECS) and receptor/second messenger signal transduction pathway for Ang-1's effect on HUVECs. The percent of apoptotic cells under control condition(0Gy) was
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