Advances in Traditional Medicine
- Volume 1 Issue 2
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- Pages.29-35
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- 2000
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- 2662-4052(pISSN)
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- 2662-4060(eISSN)
Effect of Salvia plebeia on IgE antibody mediated allergic reaction in rats
- Shin, Tae-Yong (College of Pharmacy, Woosuk University) ;
- Kim, Dae-Keun (College of Pharmacy, Woosuk University) ;
- Choi, Young-Kyun (College of Pharmacy, Woosuk University) ;
- Kim, Yong-Jin (College of Pharmacy, Woosuk University) ;
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Choi, Dong-Sung
(College of Science and Engineering, Woosuk University)
;
- Kim, Sang-Hyun (College of Pharmacy, Georgia University) ;
-
An, Nyeon-Hyung
(College of Pharmacy, Wonkwang University)
- Published : 2000.08.30
Abstract
The effect of aqueous extract of Salvia plebeia R. Br. (Labiatae) (AESP) on immunoglobulin (lgE) antibody mediated allergic reactions in rats was investigated. AESP inhibited passive cutaneous anaphylaxis (PCA) when intravenously, intraperitoneally, and orally administered. AESP dose-dependently inhibited histamine release from rat peritoneal mast cells activated by anti-DNP IgE antibody. Moreover, AESP had an inhibitory effect on anti-DNP IgE antibody induced