Korean Journal of Pharmacognosy (생약학회지)
- Volume 31 Issue 3
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- Pages.325-334
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- 2000
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Hemopoietic Effects of Rhizoma Rehmanniae Preparata on Cyclophosphamide-Induced Pernicious Anemia in Rats
Cyclophosphamide로 Rat에 유도된 악성빈혈에 대한 숙지황의 증(蒸)수에 따른 치료효능에 관한 연구
- Ha, Chang-Su (Toxicology Research Center, Research Institute of Chemical Technology) ;
- Sung, Hyun-Jea (Korea Institute of Oriental Medicine) ;
- Zee, Ok-Pyo (College of Pharmacy, Sung kyun Kwan University) ;
- Ma, Jin-Yeul (Korea Institute of Oriental Medicine)
- Published : 2000.09.30
Abstract
Rhizoma Rehmanniae Preparata is a Chinese herbal tonic. The hemopoietic effects of Rhizoma Rehmanniae Preparata(4-time steamed Jihwang, 4-time steamed double dose Jihwang, 8-time steamed Jihwang, 8-time steamed double dose Jihwang) were examined using in vitro rat(SD) model. Cyclophosphamide(150 mg/kg) was injected into experimental groups and control group to induce bone marrow suppression. Oral administration of Rhizoma Rehmanniae Preparata suppressed hormone levels of
Keywords
- Rhizoma Rehmanniae Preparata;
- hemopoietic effects;
- hormone levels;
- hematological values;
- reticulocyte