Effects of Stilbene Derivatives from Rheum undulatum on $5{\alpha}-Reductase$ Activity

$5{\alpha}-Reductase$ 활성에 미치는 종대황 스틸벤 유도체의 영향

As a series of the studies on cultivated Korean rhubarb rhizomes (Rheum undulatum), five stilbene derivatives were screened for inhibitory activity against $5{\alpha}-reductase$. Of these, desoxyrhapontigenin, rhapontigenin, and piceatannol exhibited inhibition, whereas, two other stilbene glycosides, rhaponticin and $piceatannol-3'-O-{\beta}-D-glucopyranoside$ did not show the inhibition.