Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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NMR assignments including HMBC and 1D-TOCSY data of Astragaloside I, II and Isoastragaloside I from the Roots of Astragalus membranaceus

황기뿌리에서 분리한 Astragaloside I, II 및 Isoastragaloside I의 HMBC와 1D-TOCSY data를 포함한 nmr assignments

  • 박진서 (한국한의학연구원 검사사업팀) ;
  • 김정숙 (한국한의학연구원 신약개발팀) ;
  • 김종문 (한국한의학연구원 검사사업팀) ;
  • 김진숙 (한국한의학연구원 검사사업팀)
  • Published : 2000.03.30
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Abstract

Three compounds were isolated from the roots of Astragalus membranaceus (Leguminosae). On the basis of spectroscopic evidences, the structures were characterized as $3-0-{\beta}-D-xylopyranosyl-(2',3'-O-diacetyl)-6-0-{\beta}-D-glucopyranosyl-3{\beta},6{\alpha},16{\beta},25-tetrahydroxy-20(R)$,24(S)-epoxy-cycloartane(Astragaloside I), $3-0-{\beta}-D-xylopyranosyl-(2'-O-acetyl)-6-0-{\beta}-D-glucopyranosyl-3{\beta},6{\alpha},16{\beta},25-tetrahydroxy-20(R)$,24(S)-epoxy-cycloartane(Astragaloside II), $3-0-{\beta}-D-xylopyranosyl-(2',4'-O-diacetyl)-6-0-{\beta}-D-glucopyranosyl-3{\beta},6{\alpha},16{\beta},25-tetrahydroxy-20(R)$,24(S)-epoxycycloartane(Isoastragaloside I). Full data of NMR including HMBC and 1D-TOCSY experiment of these compounds were reported for the first time.

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