The Korean Journal of Physiology and Pharmacology
- Volume 4 Issue 6
- /
- Pages.487-496
- /
- 2000
- /
- 1226-4512(pISSN)
- /
- 2093-3827(eISSN)
Comparative Effects of $PKB-{\alpha}$ and $PKC-{\zeta}$ on the Phosphorylation of GLUT4-Containing Vesicles in Rat Adipocytes
- Hah, Jong-Sik (Department of Physiology, College of Medicine, Ewha Womans University)
- Published : 2000.12.21
Abstract
Insulin stimulates glucose transport in muscle and fat cells by promoting the translocation of glucose transporter (GLUT4) to the cell surface. Phosphatidylinositide 3-kinase (PI3-kinase) has been implicated in this process. However, the involvement of protein kinase B (PKB)/Akt and
Keywords
- PI3-kinase;
- $PKC-{\zeta}$;
- $PKB-{\alpha}$;
- Phosphorylation;
- GLUT4;
- GLUT4-containig vesicles;
- Translocation;
- Insulin;
- GST-fusion proteins