Journal of Dairy Science and Biotechnology
- 제17권1호
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- Pages.1-10
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- 1999
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- 2733-4554(pISSN)
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- 2733-4562(eISSN)
Lactobacillus acidophilus GP4A가 생산하는 박테리오신의 특성 및 정제
Characteristics and Purification of Bacteriocin Produced by Lactobacillus acidophilus GP4A
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Han, Gyeong-Sik
(Department of Animal Science, College of Natural Resources, Korea University) ;
- Joo, Gwan-Seok (Department of Animal Science, College of Natural Resources, Korea University) ;
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Kim, Se-Heon
(Department of Animal Science, College of Natural Resources, Korea University)
- 발행 : 1999.05.28
초록
돼지의 장에서 분리된 Lαb. acidophilus GP4A가 생산하는 박테리오신은 typsin과 pepsin에 민감한 단백질성 물질이며 조사되어진 총 17종의균주들 중 Lactobacillus, Acinetobacter, Bacillus, Klebsiella, Streptococcus, Staphylococcus, Yersinia 속 등에 대하여 항균작용을 나타내었다. 또한 넓은 pH 조건에서도 안정하였으며
A bacteriocin produced by Lab. acidophilus GP4A isolated from fecal contents of pig was characterized. Lab. acidophilus GP4A produced a heat-stable and pH-resistant bacteriocin, which was hydrolyzed by trypsin and pepsin and active against various microorganisms. Lab. acidophilus GP4A produced bacteriocin at maximum rate when grown in MRS broth(pH 6.5