The Journal of the Korean bone and joint tumor society (대한골관절종양학회지)

The Korean Musculoskeletal Tumor Society (대한근골격종양학회)
권호 표지

Analysis of Survival and Prognostic Factors in Soft Tissue Sarcomas

연부 조직 육종의 생존 및 예후 인자 분석

  • Kim, Han-Soo (Department of Orthopaedic Surgery, Seoul National University College of Medicine) ;
  • Seong, Sang-Cheol (Department of Orthopaedic Surgery, Seoul National University College of Medicine) ;
  • Choi, In-Ho (Department of Orthopaedic Surgery, Seoul National University College of Medicine) ;
  • Chung, Chin-Youb (Department of Orthopaedic Surgery, Seoul National University College of Medicine) ;
  • Cho, Tae-Joon (Department of Orthopaedic Surgery, Seoul National University College of Medicine) ;
  • Kim, Sang-Rim (Department of Orthopaedic Surgery, Cheju Medical Center) ;
  • Jeong, Jin-Young (Department of Orthopaedic Surgery, Seoul National University College of Medicine) ;
  • Han, Il-Kyu (Department of Orthopaedic Surgery, Seoul National University College of Medicine) ;
  • Lee, Han-Koo (Department of Orthopaedic Surgery, Seoul National University College of Medicine) ;
  • Lee, Sang-Hoon (Department of Orthopaedic Surgery, Seoul National University College of Medicine)
  • 김한수 (서울대학교 의과대학 정형외과학교실) ;
  • 성상철 (서울대학교 의과대학 정형외과학교실) ;
  • 최인호 (서울대학교 의과대학 정형외과학교실) ;
  • 정진엽 (서울대학교 의과대학 정형외과학교실) ;
  • 조태준 (서울대학교 의과대학 정형외과학교실) ;
  • 김상림 (제주의료원 정형외과) ;
  • 정진영 (서울대학교 의과대학 정형외과학교실) ;
  • 한일규 (서울대학교 의과대학 정형외과학교실) ;
  • 이한구 (서울대학교 의과대학 정형외과학교실) ;
  • 이상훈 (서울대학교 의과대학 정형외과학교실)
  • Published : 1999.12.30
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Abstract

The purpose of this study was to identify the independent clinicopathologic prognostic factors of soft tissue sarcoma affecting local recurrence, metastasis and survival. Retrospectively collected data from 130 patients with soft tissue sarcoma were analyzed. Patient, tumor and pathologic factors were analyzed by univariate and multivariate methods for the endpoints of local recurrence, metastasis and survival. In univariate analysis, wide surgical margin, adjuvant radiotherapy and age younger than 40 years reduced local recurrence. Tumor size larger than 5cm was related with a higher rate of metastasis. Patients with metastasis at initial presentation and with a large tumor size had a low survival rate. In multivariate analysis, adjuvant radiotherapy and young age were significantly correlated with a low local recurrence rate. In conclusion, patients with metastasis at initial presentation and a large tumor size had a reduced survival rate. Independent adverse prognostic factors for local recurrence were old age and not undergoing adjuvant therapy.

Keywords

Acknowledgement

Supported by : 서울대학병원