Tuberculosis and Respiratory Diseases
- Volume 47 Issue 3
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- Pages.347-355
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- 1999
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- 1738-3536(pISSN)
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- 2005-6184(eISSN)
Increased Expression of Phospholipase C-$\gamma1$ Activator Protein, AHNAK in Human Lung Cancer Tissues
인체 폐암조직에서 Phospholipase C-$\gamma1$ 의 활성화 단백, AHNAK의 발현양상
- Oh, Yoon-Jung (Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine) ;
- Park, Chun-Seong (Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine) ;
- Choi, So-Yeon (Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine) ;
- Cheong, Seong-Cheoll (Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine) ;
- Lee, Sun-Min (Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine) ;
- Hwang, Sung-Chul (Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine) ;
- Lee, Yi-Hyeong (Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine) ;
- Hahn, Myung-Ho (Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine) ;
- Lee, Kyi-Beom (Department of Anatomic Pathology, Ajou University School of Medicine) ;
- Ryu, Han-Young (Department of Thoracic Surgery, Ajou University School of Medicine) ;
- Ha, Mahn-Joon (Laboratory of Medical Genetics, Ajou University School of Medicine) ;
- Bae, Yoon-Su (Department of Biological Sciences, Ewha Womans University) ;
- Rhee, Seo-Goo (Laboratory of Cell Signaling, National Institutes of Health)
- 오윤정 (아주대학교 의과대학 호흡기내과학교실) ;
- 박준성 (아주대학교 의과대학 호흡기내과학교실) ;
- 최소연 (아주대학교 의과대학 호흡기내과학교실) ;
- 정성철 (아주대학교 의과대학 호흡기내과학교실) ;
- 이선민 (아주대학교 의과대학 호흡기내과학교실) ;
- 황성철 (아주대학교 의과대학 호흡기내과학교실) ;
- 이이형 (아주대학교 의과대학 호흡기내과학교실) ;
- 한명호 (아주대학교 의과대학 호흡기내과학교실) ;
- 이기범 (아주대학교 의과대학 해부병리학교실) ;
- 류한영 (아주대학교 의과대학 흉부외과학교실) ;
- 하만준 (아주대학교 의과대학 의학유전학교실) ;
- 배윤수 (이화여대 생물학교실) ;
- 이서구 (미국국립보건원 심폐혈액질환연구소)
- Published : 1999.09.30
Abstract
Background: Phospholipase C(PLC) plays a central role in cellular signal transduction and is important in cellular growth, differentiation and transformation. There are currently ten known mammalian isozymes of PLC reported to this date. Hydrolysis of phosphatidylinositol 4,5-bisphosphate(
배경: Phospholipase C(PLC)는 세포의 성장, 분화, 변형(transformation)과 관련된 세포내 신호 전달과정에 중추적인 역할을 하는 효소이다. 이들 중 PLC-