Tuberculosis and Respiratory Diseases
- Volume 46 Issue 3
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- Pages.409-413
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- 1999
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- 1738-3536(pISSN)
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- 2005-6184(eISSN)
A Case of Primary Malignant Melanoma in the Mediastinum
종격동 종양이 주병소인 악성 흑색종 1예
- Koo, Bon-Sam (Department of Internal Medicine, Kosin Medical College) ;
- Jung, Yong-Seuk (Department of Internal Medicine, Kosin Medical College) ;
- Park, Hee-Bag (Department of Internal Medicine, Kosin Medical College) ;
- Ok, Cheol-Ho (Department of Internal Medicine, Kosin Medical College) ;
- Jang, Tae-Won (Department of Internal Medicine, Kosin Medical College) ;
- Jung, Man-Hong (Department of Internal Medicine, Kosin Medical College) ;
- Lee, Jae-Sung (Department of Thoracic Surgery, Kosin Medical College) ;
- Chun, Bong-Kwon (Department of Pathology, Kosin Medical College)
- 구본삼 (고신의대 내과학교실) ;
- 정용석 (고신의대 내과학교실) ;
- 박희백 (고신의대 내과학교실) ;
- 옥철호 (고신의대 내과학교실) ;
- 장태원 (고신의대 내과학교실) ;
- 정만홍 (고신의대 내과학교실) ;
- 이재성 (고신의대 흉부외과학교실) ;
- 천봉권 (고신의대 해부병리학교실)
- Published : 1999.03.30
Abstract
Malignant melanoma develops from the melanocyte and the most common primary site is skin, followed by mucosa and retina. Even though any other tissue where melanocytes reside could be the primary site of the malignant melanoma, the one developed in the mediastinum is rarely reported. We experienced a patients of 54 years old woman whose initial symptom was progressive dyspnea for one month, and proved to have the anterior mediastinal mass with pleural effusion and the small mass in the abdominal soft tissue. The needle aspiration biopsy from the mediastinal mass showed the consistent findings with malignant melanoma. We concluded the mediastinum was the primary site of the malignant melanoma of this patient because we couldn't find any other evidence of primary tumor in skin, oral and gastrointestinal mucosa, and retina. She has been treated with combined chemotherapy with dacarbazine, cisplatin and vinblastine. Her symptom was improved after chemotherapy and follow up chest CT after three cycles of chemotherapy showed the decreased tumor size in the mediastinum.