Restorative Dentistry and Endodontics
- 제24권1호
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- Pages.180-186
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- 1999
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- 2234-7658(pISSN)
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- 2234-7666(eISSN)
치수에서 Eugenol이 iCGRP(immunoreactive calcitonin gene-related peptide)의 분비 조절에 미치는 영향
EFFECT OF EUGENOL ON REGULATION OF iCGRP RELEASE FROM THE BOVINE DENTAL PULP
- Oh, Won-Mann (College of Dentistry, Institute of Dental Science Chonnam Nat. Uni.) ;
- Choi, Nam-Ki (College of Dentistry, Institute of Dental Science Chonnam Nat. Uni.) ;
- Kim, Sun-Hun (College of Dentistry, Institute of Dental Science Chonnam Nat. Uni.)
- 발행 : 1999.04.06
초록
Eugenol has been reported to reduce odontogenic pain and is known to have a structure similar to capsaicin, a potent stimulant of certain nociceptors. We have hypothesized that the analgesic effect of eugenol may be due, in part, to inhibition of capsaicin-sensitive nociceptors. To test this hypothesis, we evaluate whether eugenol inhibits capsaicin-sensitive release of immunoreactive calcitonin generated peptide(iCGRP) from bovine dental pulp. Freshly extracted bovine incisors were transported to the lab. on ice, Spilitted and pulp tissue was removed. The tissue was chopped into 200