한국응용과학기술학회지 (Journal of the Korean Applied Science and Technology)
- 제16권4호
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- Pages.293-298
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- 1999
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- 1225-9098(pISSN)
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- 2288-1069(eISSN)
DOI QR Code
In vitro에서 Sulfonamide의 Dual Action에 의한 항균특성
Antibiotics Characteristics by Dual action of Sulfonamide Agents In vitro
- Jung, Duck-Chae (Dept. of Chemistry, University of InChon) ;
- Hwang, Sung-Kyu (Dept. of Chemical Engineering, Myong-Ji Univ.) ;
- Kim, Jong-Woan (Dept. of Chemical Engineering, Myong-Ji Univ.) ;
- Seok, Ji-Hyun (Dept. of Environmental Health, Yong In Univ.) ;
- Kim, Woon-Kyeom (Dept. of Fine chemistry, Seoul National Univ. of Technology)
- 발행 : 1999.12.31
초록
Dual-action agents are unique chemical entities comprised of two different types of antibacterial compounds covalently linked together in a single molecule in such a way that both components are able to exert their bactericidal properties. Crosslinked sulfadiazine-sulfacetamide such as antibiotics synthesized by crosslingking reaction such as glutaraldehyde. These structures of the compounds were confirmed by IR, NMR. 4 strains of Gram(+) and Gram(-) revealed effective susceptibility to synthetic crosslinked sulfadiazine-sulfacetamide.
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