Korean Journal of Psychosomatic Medicine (정신신체의학)
- Volume 7 Issue 2
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- Pages.241-246
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- 1999
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- 1225-6471(pISSN)
Two Cases of Delirium Induced by Transdermal Scopolamine(Kimite$^{(R)}$ )
Transdermal Scopolamine(Kimite$^{(R)}$ )으로 인해 유발된 섬망 2례
- Woo, Haing-Won (Department of Psychiatry, College of Medicine, Ewha Womens University) ;
- Lim, Weon-Jeong (Department of Psychiatry, College of Medicine, Ewha Womens University) ;
- Lee, Yu-Jin (Department of Psychiatry, College of Medicine, Ewha Womens University)
- Published : 1999.12.15
Abstract
Delirium is a syndrome characterized by impairement of consciousness, disorientation, disturbance of sleep-wake cycle, memory impairement, disturbance of perception. It is induced by many causes, which are CNS diseases(head trauma, vascular disease, brain tumor, etc), medical diseases(metabolic disorder, endocrine disturbance, cardiovascular disease) and drugs(anticholinergics, anticonvulsant, antipsychotics, cimetidine etc). Transdermal scopolamine which is usually used to prevent motion sickness has anticholinergic property, and so it can induce delirium. The authors report two cases of delirium induced by transdermal scopolamine. The cases shared common characteristics which were as follows : 1. All of two patients were elderly women. 2. Delirium symptom was abruptly occurred during trip after attaching scopolamine patches. 3. Delirium symptom was rapidly improved within 2-3 days. It is important to educate for both users and managers about directions for transdermal scopolamine patch usage to prevent delirium. And careful history taking is needed to diagnose delirium induced by transdermal scopolamine accurately.
섬망은 두부손상, 혈관성 질환, 뇌종양 등의 중추신경계 질병뿐 아니라 여러 가지 신체 질병(대사 장애 및 내분비장애, 감염, 심혈관 질병)과 약물에 의해 야기되는 각성 수준의 감퇴, 지남력 장애, 수면-각성 주기 장애, 기억력 장애, 지각장애 등을 특징으로 하는 증후군이다. 1) 섬망을 일으킬 수 있는 약물의 하나인 scopolamine(Kimite