Spontaneous Hydronephrosis in $C57BL/KsJ-Lepr^{db}/Lepr^{db}$ Mouse, an animal Model for Human NIDDM

인슐린비의존형 당뇨병 마우스 $C57BL/KsJ-Lepr^{db}/Lepr^{db}$ 의 수신증 발생 예

  • Jeong, Su-Yeon (Department of Laboratory Animal Medicine, Medical Research Center, Yonsei University College of Medicine) ;
  • Yun, Young-Min (Department of Laboratory Animal Medicine, Medical Research Center, Yonsei University College of Medicine) ;
  • Seong, Je-Kyung (Department of Laboratory Animal Medicine, Medical Research Center, Yonsei University College of Medicine)
  • 정수연 (연세대학교 의과대학 실험동물부) ;
  • 윤영민 (연세대학교 의과대학 실험동물부) ;
  • 성제경 (연세대학교 의과대학 실험동물부)
  • Published : 1999.12.01

Abstract

Spontaneous hydronephrosis was found in a 19 month-old female C57BL/KsJ-Lep $r^{db}$ / Lep $r^{db}$ mouse. We described the gross and histological appearance of spontaneous in db mouse The left kidney was dilated and filled with urine. Microscopically the renal pelvis was remarkedly dilated and the renal cortex and renal papilla were flattened.

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