Korean Journal of Veterinary Pathology (한국수의병리학회지)
- Volume 3 Issue 2
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- Pages.83-85
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- 1999
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- 1226-766X(pISSN)
Effects of 7,12-dimethylbenz[A]-anthracene(DMBA) on the Spleen in Syrian Golden Hamsters after Subcutaneous Injections
- Son, W.C. (Biotech Research Institute, LG Chem) ;
- Kamino, K. (Institute of cell and molecular pathology, Hannover Medical School)
- Published : 1999.12.01
Abstract
Weekly subcutaneous injection of7 ,12-dimethylbenz[a]anthracene(DMBA) at a dose level of 0.25kg/mg body weight induced proliferative lesions in the spleen of syrian golden of syrian In addition, subcutaneous tumors at injection sites were observed. The splenic lesions included stromal hyperplasia and hacmangioma-like lesion.
Keywords
- 7,12-dimethylbenz[A]-anthracene(DMBA);
- syrian golden hamster;
- spleen;
- stromal hyperplasia;
- hemangioma-like lesion