Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Hematological Changes in Dogs Administrated Excessive Garlic-extracts

과량의 마늘투여로 인한 개의 혈액학적 변화

  • Keun-woo Lee (College of Veterinary Medicine, Kyungpook National University) ;
  • In-ho Jang (College of Veterinary Medicine, Kyungpook National University) ;
  • Kwang-ho Jang (College of Veterinary Medicine, Kyungpook National University)
  • Published : 1999.12.01
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Abstract

마늘은 백합과 식물로서 인류의 식생활에서 중요한 역할을 할 뿐 아니라 최근에는 항암작용을 가진 것으로도 알려져 세계적으로 많은 연구가 수행되고 있다. 그러나 같은 백합과 식물인 양파의 경우 과량 섭취시 개에서 용혈성 빈혈이 유발된다는 것은 잘 알려진 사실이지만 마늘의 경우 이러한 부작용에 관한 보고는 전혀 없는 실정이다. 따라서 본 연구에서는 체중 25 kg 이상의 성견을 대상으로 마늘 추출액을 투여한 결과 다음과 같은 성적을 얻었다. 총적혈구수(RBC), 헤모글로빈(Hb)함량, 혈구용적(PCV), 평균적혈구용적(MCV), 평균적혈구혈색소농도(MCHC)는 실험기간 중 유의한(P＜0.05) 감소경향을 나타내었다. GSH 함량은 6일째 유의한(P<0.01)증가를 나타내었다. 본 실험 성적의 결과 과량의 마늘 투여시에도 양파에서와 동일한 용혈성 빈혈이 발생되는 것으로 생각된다.

Keywords

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