Evaluation of Modified Extraluminal Prostheses Applied to the Trachea in Dogs

개의 기관에 적용한 변형제작한 기관외보철물의 평가

  • Published : 1999.06.01

Abstract

The purpose of the present study was to evaluate the easiness of suture and fixation of modified total ring prostheses (m-TRP). Twelve healthy dogs (B.W.2-10 kg) were randomly assigned to three groups. In group A (3 dogs), total ring prostheses was fixed by penetrating a suture material through tracheal mucosa. In group B (3 dogs), TRP was fixed by suturing on tracheal cartilage and muscular layer not penetrating through tracheal mucosa. m-TRP was applied to the cervical portions (group M-C,3 dogs), and thoracic portions (group M-T,3 dogs). Operating time of group M-C (37.33$\pm$6.80 min.) was shorter than those of groups B (83.33$\pm$8.50 min.) and A (63.33$\pm$11.06 min.) (p<0.01). Clinical complications were minimal and limited to mild, short-term hematoma, vomiting, edema, and inflammation. Coughing remarkably decreased in group B rather than group A. Dyspnea was not showed in group A, B, and M-C, but group M-T had a mild dyspnea. Gross postmortem findings were similar in all groups. Mild adhesions were present between prostheses and adjacent structures, but tracheal lumen was clean. Severe adhesions were present where m-TRP had been applied in the thoracic portions. Histopathologic abnormalities included mild to moderate adventitial and periprosthetic fibrosis and mild adventitial inflammation. The present study indicated that m-TRP were easier in suture and fixation than TRP and had no differences in support for trachea and side effects.

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References

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