Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
권호 표지

Effects of Fermented Milk Feeding on Function and Suppression of Aluminum Accumulation in Kidney of Rat

젖산균 발효유 섭취가 흰쥐의 신장내 알루미늄 축적억제와 신장기능에 미치는 영향

  • 김중만 (원광대학교 생명자원과학대학) ;
  • 박성수 (송원전문대학 식품영양과) ;
  • 백승화 (충북도립옥천대학 식품공업과) ;
  • 정동현 (축산협동조합중앙회 한국양봉 인천공장) ;
  • 최용배 (원광대학교 생명자원과학대학) ;
  • 신용서 (원광대학교 생명자원과학대학) ;
  • 한성희 (원광대학교 생명자원과학대학) ;
  • 홍가형 (원광대학교 생명자원과학대학)
  • Published : 1999.02.01
Download PDF
⟨ Previous Next ⟩

Abstract

This study was performed to evaluate the effects of the supplementation of lactic acid bacterias (LAB; S. thermophilus, L. acidophilus) aluminum accumulation and function kidney in rats treated with 250 g/g aluminum sulfate for 4 weeks. Fifty male Sprague Dawley strains were divided into five groups according to the types of supplement. the control, S. thermophilus culture group(A), autoclaved S. thermophilus culture(B), L. acidophilus culture group(C) and autoclaved L. acidophilus(D). The weight gain was increased by supplementation of S. thermophilus culture(A), autoclaved S. thermophilus culture(B), L. acidophilus culture(C), autoclaved L. acidophilus culture(D), especially by supplementation of S. thermophilus cultured(A) as compared to control group. The amount of water intake was increased in control group as compared to the LAB supplemented group. The content of aluminum were decreased 19.57%, 31.25%, 37.10%, and 32.40% in kidney after supplementation of non autoclaved culture group (A,C), and autoclaved group(B,D) respectively, as compared to control group. Water balance, urine volume, and excretion of sodium and potassium decreased in LAB supplemented group and control group. Excretion of creatinine increased in control group and tendency to increased in LAB supplemented group. In conclusion, the effect of suppression of aluminum accumulation was more effective in sup plementation of S. thermophilus culture(A), and L. acidophilus culture(C) than autoclaved S. thermo philus culture(B), and L. acidophilus culture(D).

Keywords

References

  1. Fd. Technol. v.39 Aluminum content of the American diet Greger, J. L.
  2. Am. J. Clin. Nutr. v.33 Metabolism and toxicity of aluminum in renal failure Alfrey, A. C.;Hegg, A.;Craswell, P.
  3. Editorial. N. Engl. J. Med. v.310 Aluminum intoxication Alfrey, A. C.
  4. Science v.180 Brain aluminum distribution in Alzheimer's disease and experimental neurofibrillary degeneration Crapper, D. R.;Krishnan, S. S.;Dalton, A. J.
  5. Lancet v.2 Selective loss of cholinergic neurones in Alzherimer's disease Davies, P.;Malonet, A. F. J.
  6. Sciece v.217 Intraneuronal aluminum accumulation in amyrotrophic lateral sclerosis and Parkinsonism dementia of Guam. Perl, D. P.;Gaidusek, K. C.;Garruto, R. M.;Unagihara, R. T.;Gibbs, C. J.
  7. Lancet v.1 Osteomalacia dialysis osteodystrophy: Evidence for a sater-bone aetiological agents,Probably Aluminum Ward, M. K.;Feest, T. G.;Eills, M. A.;Parkinson, I. S.;Kerr, D. N. S.
  8. 小兒科臨床 v.33 降一郞;管長彦;手鶴久;黑島敏方;小平番士;鈴木振一;寺島經男;務台方彦
  9. J. National Cancer Institude v.64 Effect of diet and Lactobacillus acidophillus supplements in human fecal bacteria enzyme Goldin, B. R.;Swenson, L.;Dwyer, T.;Sexton, M.;Gorbach, S. L.
  10. Appl. Environ. Microbiol. v.49 Assimilation of cholesterol by Sactobacillus acidoplilus Gilliand, S. E.;Nelson, C. R.;Maxwell, C.
  11. 腸內 floraと 發癌(光岡之足編) 荒정幸一郞;室田一也;早川邦産;片岡元行;光岡之足
  12. 乳酸菌の抗癌效果 Shahani, K. M.
  13. Cancer Res. v.35 The epidemiology of large bowel cancer Wynder, E. L.
  14. Agricultural Chemictry and Biotechnology v.37 Survival rate of lactic acid bactera and the change of β-galactosidase activity in commercial yogurts under the acidic conditions Shin, Y. S.;Sung, H. J.;Kim, D. H.;Lee, K. S.
  15. Korean J. Food Sci. Technol. v.26 Inhibitory effect of lactic acid bacteria and its metabolites on the growth of Staphulococcus aureus Kim, S. H.;Sung, H. J.;Shin, Y. S.;Kim, D. H.;Lee, K. S.
  16. Kor. J. Appl. Microbiol. Bioeng. v.4 Isolation of cadmium-tolerant bacteria and accumulation of cadmium into bactera Cell Kim, Y. B.;Lee, S. R.
  17. Annu. Rev. Microbiol. v.43 Role of cellular design in bacterial metal accumulation and mineralization Beveridge, T. J.
  18. Studies on the survivals of lactic acid bacteria and its effects in the conditions of intestine. Ph'D thesis Shin, Y. S.
  19. Kor. J. Vet. Publ. Hith. v.18 Effects of Lactibacillus acidophilus-fermented milk on accumulation of cadmium in rats Cho, Y. C.;Jun, M. H.
  20. At. Absorpt. Newsl. v.13 Rapid acid dissolution of plant tissue for cadmium determination by atomic absorption of spectrophotometry Gange, T. J.;Page, A. L.
  21. Quantitative clinical chemistry methods v.2 Phillips, R. A.;Peter, J. P.;Vanslyke, D. D.(eds.)
  22. SAS Series Package SAS
  23. Acta Pharmacol. Toxicol. v.59 Effects of dietary factors on GI: Cd absorption in mice Schrager, L.;Andersen, O.;Nielsen, J. B.
  24. Jap. J. Hyg. v.34 The metabolism of 109 Cd administered to mice previously given an oral dose of cadmium Taquchi, T.;Suzuki, S.
  25. Aluminum contents in foods and influences of aluminum compound on the physiological and the histological changes of rat. Ph.D. thesis Han, S. H.
  26. A first line of defense against cadmium toxicity. Department of Biochemistry Singhal, R. K.;Anderson, M. E.;Meister, A.
  27. Environmetal Research v.42 Dietary fiber and heavy metal ritintion in the rat Rose, H. E.;quarterman, J.
  28. Effects of vitamin C and Fe, Cd metabolism Fox, M. R. S.
  29. Clin. Chem. v.25 Metabolic balance of aluminum studies in six men Gorsky, J. E.;Dietza, A. A.;Spencer, H.;Osis, D.
  30. The kidney Brener, B. M.;Rector, F. C.
  31. J. Am. Med. Assoc. v.174 Hypotensive agents and presser substances Laragh, J. H.;Angers, M.;Kelly, W. G.;Liberman, S.
  32. Am. J. Physiol. v.49 Studies on the nervous control of the kidney in relation to diuresis and urinary secertion Marshall, E. K. J.;Kolls, A. C.
  33. J. Clin. Inves. v.56 Effects of acute unilateral renal denervation in the rat Bello-Reuss, E.;Colindress, R. e.;Pastoreza-Munoz, E.;Muleller, R. A.;Gottschalk, C. W.
  34. Neurotoxcol. v.1 Aluminum metabolism in uremia Alfrey, A. C.
  35. Ann. Rev. Physiol. v.42 Potassium transport in the nephron Giebish, G.;Suanton, B.
  36. N. Engl. J. Med. v.296 Gastrointestional absorption of aluminum from aluminumcontaing antacids Kaehny, W. K.;Hegg, A. P.;Alfrey, A. C.