Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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Effects of Mind Tonic Drinks on Sociopsychological Stress

사회.심리적 스트레스에 미치는 마인드 토닉(Mind Tonic) 음료의 영향

  • 최진호 (부경대학교 식품생명공학부 생화학연구실) ;
  • 김대익 (부경대학교 식품생명공학부 생화학연구실) ;
  • 박수현 (부경대학교 식품생명공학부 생화학연구실) ;
  • 김동우 (부경대학교 식품생명공학부 생화학연구실) ;
  • 조원기 (조아제약(주)) ;
  • 유병팔 (텍사스대학교 의과대학 생리학과)
  • Published : 1999.10.01
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Abstract

The effects of anti-stress mind tonic (ASMT) drink (ASMT-0.1% and ASMT-0.5% concentration) were tested for the anti-stress action. ICR male mice (20$\pm$2 g) were fed with basic experimental diets free access to water containing these ingredients for 18 days. Psychological stress/sociopsychological stress were exposed by foot-shock for 1 hour for 3 days. Both ASMT-0.1 and ASMT-0.5 groups in the sociopsychological stress resulted in a significant decrease of 19.1% and 41.9% in plasma corticosterone (CS) secretion compared with psychological stress (control group). Noradrenaline (NA) secretions in the brain were significantly increased 23.4% and 35.9%, respectively, in ASMT-0.1 and ASMT-0.5 groups compared with control group. MHPG-SO4 (3-Methoxy-4-hydroxyphenylethyleneglycol sulfate) levels in the brain resulted in a marked decreases of 27.1% and 19.6%, respectively in ASMT-0.1 and ASMT-0.5 groups. NA/MHPG-SO4 ratios in the brain of ASMT-0.1 and ASMT-0.5 groups resulted in a significantly increase of about 70% compared with control group. These suggest that mind tonic anti-stress drink can effectively ridded the sociopsychological stress.

Keywords

References

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