Archives of Pharmacal Research
- Volume 22 Issue 4
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- Pages.380-383
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- 1999
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Synthesis and In Vitro Cytotoxicity of 1-Azanthraquinone-3-Carboxamides
-
Lee, Hee-Soon
(College of Pharmacy, Chungbuk National University)
;
- Lee, Chang-Wook (College of Pharmacy, Chungbuk National University) ;
- Yang, Sung-Il (College of Medicine, Kunkuk University)
- Published : 1999.08.01
Abstract
Five 1-azzanthraquinone-3-carboxamides were synthesized and evaluated in vitro cytotoxicity against four human cancer cell lines. The most active compound, 7b, exhibited cytotoxic activity comparable to doxorubicin.
Keywords
- Drug resistance;
- Chemotherapy;
- Azaanthraquinone;
- Cytotoxic activity;
- Doxorubicin;
- Acridine-4-carboxamide