Effects of Rheum Plants on Blood Platelet Aggregation

대황류생약의 혈소판응집억제작용

  • Published : 1999.04.01

Abstract

In order to clarify the anti-Ohyul activity of rhubarb, we investigated the effects of water extract from rhizomes of four different rhubarb on blood platelet aggregation induced by arachidonic acid, ADP, collagen and PAF in vitro. The cultivated Korean rhubarb rhizomes (Rheum undulatum) exhibited the most potent inhibitory action on the aggregation induced by arachidonic acid and also among the four fractions, stilbene components containing part showed strong inhibitory action. These inhibitory effect may partially contributed to anti-Ohyul activity of rhubarb.

Keywords

References

  1. 和漢藥百科圖鑑(Ⅰ) 難波恒雄
  2. 漢方藥の藥能と藥理 谿 忠人
  3. Yakugaku Zasshi v.87 no.9 Studies on the purgative substance Ⅰ, isolation of sennoside A, one of the most active principles from rhubarbs Miyamoto, M.;Imai, S.;Shinohara, M.;Fusioka, S.
  4. Yakugaku Zasshi v.100 no.4 Effect of rhubarb (Rhei Rhizoma) extract on urea nitrogen and amino acid metabolism after the administration Shibutani, S.;Nagasawa, T.;Oura, H.
  5. Chem. Pharm. Bull. v.31 no.8 Effect of extract from Rhei Rhizoma on adenine-induced renal failure in rats Yokozawa, T.;Zheng, P. D.;Oura, H.
  6. 和漢醫藥學會誌 v.2 대황성분 RG-tannin의 항정신작용 植木昭和
  7. 和漢藥 symposium v.16 春田良典
  8. Ⅱ Farmaco (Ed, Sci.) v.33 Analgesic activity of some phenolic components in rhubarb Darias, V.
  9. Indian Journal of Chemistry v.22B Spasmolytic principle from Rheum webbianum Chandhari, M.;Jain, G. K.;Sarin, J. P.;Khanna, N. M.
  10. Arch. Pharm. Res. v.17 no.1 Antitumor activity of some phenolic components in plants Ryu, S. Y.;Choi, S. U.;Lee, C. O.;Lee, S. H.;Ahn, J. W.;Zee, O. P.
  11. Journal of Traditional Medicines v.14 Study on anti-Oketsu activity of rhubarb Ⅰ. Pharmacological efficacy of rhubarb (Rheum undulatum L.) cultivated in Korea Kubo, M.;Ko, S. K.;Harima, S.;Matsuda, H.;Kim, I. H.
  12. Arch. Pharm. Res. v.21 no.6 Anticomplementary activity of stillbenes from medicinal plants Oh, S. R.;Rhu, S. Y.;Park, S. H.;Jung, K. Y.;Lee, I. S.;An, K. S.;Lee, J. J.;Lee, H. K.
  13. J. Physiol. v.168 Born, G. V. R.;Cross, M. J.