BMB Reports
- Volume 32 Issue 4
- /
- Pages.339-344
- /
- 1999
- /
- 1976-670X(eISSN)
Influence of Ginsenosides on the Kainic Acid-Induced Seizure Activity in Immature Rats
- Park, Jin-Kyu (Korea Ginseng & Tobacco Research Institute) ;
- Jin, Sung-Ha (Korea Ginseng & Tobacco Research Institute) ;
- Choi, Keum-Hee (Korea Ginseng & Tobacco Research Institute) ;
- Ko, Ji-Hun (Korea Ginseng & Tobacco Research Institute) ;
- Baek, Nam-In (Department of Life Sciences and Institute of Life Science & Resources, Kyunghee University) ;
- Choi, Soo-Young (Department of Genetic Engineering, Division of Life Sciences, Hallym University) ;
- Cho, Sung-Woo (Department of Biochemistry, College of Medicine, University of Ulsan) ;
- Choi, Kang-Ju (Korea Ginseng & Tobacco Research Institute) ;
- Nam, Ki-Yeul (Korea Ginseng & Tobacco Research Institute)
- Published : 1999.07.31
Abstract
We studied the effects of ginsenosides in immature rats based upon the previous results that ginseng has a suppressive or anticonvulsive activity. To examine the suppressive effect of ginsenosides on kainic acid-induced seizures, the severities and frequencies were observed for 4 h after injection of kainic acid (KA; i.p., 2 mg/kg b.w.) using 10-day-old male Sprague-Dawley rats (