한국임상약학회지 (Korean Journal of Clinical Pharmacy)
- 제9권1호
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- Pages.35-43
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- 1999
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- 1226-6051(pISSN)
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- 2508-786X(eISSN)
외과계 입원환자에 대한 Vancomycin의 약물사용 평가
Drug Use Evaluation of Vancomycin in Hospitalized Patients of Surgery Departments
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Lee, Young Mee
(Division of Pharmaceutical Services, Samsung Medical Center) ;
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Choi, Kyung Eob
(Division of Pharmaceutical Services, Samsung Medical Center)
- 발행 : 1999.05.01
초록
Over the last 50 years, a number of antibiotic agents have been developed and clinically used in the area of infectious diseases. Due to antimicrobial resistance problems and increasing health care costs, the rational use of antibiotics has been required. As a drug of choice to treat infections caused by MRSA, vancomycin has been extensively prescribed since the late 1970's. Recently, reports of vancomycin-resistant organisms such as VRE and VRSA have been increased to draw medical concerns. The objectives of this study were to evaluate the rational use of vancomycin and the appropriateness of the Restrictional Program of Antibiotic Utilization (RPAU) which has been operated at Samsung Medical Center. A retrospective chart review was performed in 132 hospitalized patients treated with vancomycin in the surgery departments from. January to June 1998. The guidelines of ASHP and HICPAC for vancomycin were modified and used as our criteria to determine the vancomycin DUE. In one hundred out of the patients, uses of vancomycin were approved by the Department of Infectious Diseases (DID) based on the RPAU. Vancomycin was appropriately used in