Studies on the effects of Sojeokbaekchoolsan on the bleomycin induced pulmonary fibrosis and the antitumor activity

소적백출산(消積白朮散)이 Bleomycin의 부작용감소(副作用減少)와 항암효과(抗癌效果)에 미치는 영향(影響)

  • Published : 1999.12.30

Abstract

l. Sojeokbaekchoolsan compound treatment decreased pulmonary fibrosis induced by Bleomycin. 2. At 1 and 2 days after bleomycin treatment, Sojeokbaekchoolsan compound treatment decreased the number of neutrophils in bronchoalveolar lavage than those of bleomycin alone treatment. 3. Sojeokbaekcoolsan compound treatment increased the Fc receptor mediated rosette activity of alveolar macrophage decreased by bleomycin treatment. 4, At 10 days after bleomycin treatment, Sojeokbaekchoolsan compound treatment decreased the lipid peroxidation of lung tissue than those of bleomycin alone treatment. 5. Anti-tumor activity of Sojeokbaekchoolsan and bleomycin compound group was higher than those of bleomycin alone treated group to ascitic tumor caused by Sarcoma-180 tumor cells.

Keywords

References

  1. 發がん 西村進(외)
  2. 內科學(下卷) v.下 李文鎬(외)
  3. Studies on Bleomycin Cancer v.20 Umezawa, H.;Ishizuka, M.;Maeda, K.;Takeuchi, T.
  4. 東洋醫學 v.18 no.2 消積白朮散의 抗癌效果 및 Cisplatin副作用에 미치는 影響 白承學
  5. 大田大韓醫大博士學位論文 消積白朮散의 抗癌, 免疾增强 效果 및 Cisplatin의 腎臟毒性 抑制에 미치는 影響에 對한 硏究 趙成基
  6. 大田大韓醫大博士學位論文 消積白朮散이 생쥐의 細網內皮系遮斷 및 體液性 免疾抑制에 미치는 影響 梁緖賢
  7. 大田大韓醫大碩士學位論文 消積白朮散이 免疾細胞의 動態, 大食細胞의 走化性 및 附着能에 미치는 影響 朴太瑄
  8. 病理學 孫泰重
  9. 腫瘍學 서울大學校醫科大學
  10. 病理學 金春元
  11. Nature v.261 Short-term screenibg tests for carcinigens Bridges, B.A.
  12. Ann Rev Biochem. v.44 Chemical carcinogenesis Heidelberger, C.
  13. 現代中國의 癌治療法 洪元植(譯)
  14. 現代醫學における漢方藥劑 有地滋
  15. Hosts defence mechanisms and their modification by cancer chemothrapy. In methods in Cancer Research Hersh, E.M.;Ereish, E.J.
  16. Tumor Immunol. v.69 Tumor immunology and immunotheraohy Madewell, B.R.
  17. 中醫雜誌 v.31 no.11 灸法抗腫瘤及化療副作用的硏究進展 王少錦
  18. 中國中西結合雜誌 v.12 no.3 中醫藥對腫瘤放化療的增敏減毒作用 張代釗(외)
  19. 中醫雜誌 v.31 no.1 中醫中藥配合放射治療癌症開況 孫華麗;余桂淸
  20. 浙江中醫雜誌 v.26 no.1 中醫藥防治癌的體會 王濟民;王俊茹
  21. 丹溪心法 v.68 朱震享
  22. 景岳全書 張景岳
  23. 醫余必讀 李中梓
  24. 中醫雜誌 六味地黃湯防治腫瘤的實驗硏究 姜廷良(외)
  25. 浙江中醫學院學報 v.3 扶正培本法在腫瘤臨床的應用 徐龍生(외)
  26. 方藥合編解說 申載鏞
  27. 中醫外科學 顧伯康(외)
  28. 辨症診治槪要 白洪龍
  29. 六科準繩(券3) v.3 王肯堂
  30. 浙江中醫雜誌 v.7 惡性腫瘤服藥方法的實驗硏究 邱추信(외)
  31. 上海中醫學雜誌 v.1 晩期惡性腫瘤的異病同治 邱추信(외)
  32. 中西醫結合雜誌 v.8 人蔘抗小鼠手術應激的細胞免疫調節效應 楊貴貞(외)
  33. 中西醫結合雜誌 v.7 惡性腫瘤氣虛, 陰虛證患者免疫功能觀察 許繼平(외)
  34. 上海中醫藥雜誌 v.2 扶正培本法治療中, 晩期遠發性肝癌31例 林宗廣
  35. 上海中藥雜誌 v.8 益氣養陰法對細胞免疫的作用 伊和姿
  36. 中西醫結合雜誌 v.5 扶正抗癌方僞主結合和療治療術后晩期胃癌的 療效 觀察 玉冠延(외)
  37. 中草藥 v.20 扶正固本中藥復方對小鼠巨筮細胞和B細胞免疫功能的作用 玉淑英(외)
  38. 中草免疫 劉正才
  39. 中西醫結合雜誌 v.7 健脾理氣,淸熱解毒,軟堅化痰方劑治療晩期肝癌的臨床觀察及 實驗硏究 楊金坤(외)
  40. 方劑學 許濟群
  41. 天然藥物大事典(上卷) v.上 金在佶
  42. 申氏本草學 申佶求
  43. 本草學 李尙仁
  44. 治癌中藥及處方 葉銘洪
  45. 經史證類大觀本草 唐愼微
  46. 本草求眞, 宏業書局 黃宮肅
  47. 韓藥臨床應用 李尙仁(외)
  48. 高麗人蔘學會誌 v.3 no.1 人蔘의 藥理作用 洪思岳
  49. 趙英植博士華甲記念論文集 數種漢藥材가 制癌劑 및 glucocorticoid의 抗體生産抑制作 用에 미치는 影響 金光湖(외)
  50. 大韓免疫學會誌 v.1 no.1 3-Methylcholanthrene에 依하여 誘導된 腫瘍마우스의 綿羊赤血球에 對한 免疫反應 鄭憲鐸(외)
  51. 大韓醫學協會誌 v.27 no.6 高麗人蔘이 3-Methylcholanthrene의 發癌能에 미치는 影響 河大有(외)
  52. 人間醫學 v.3 人蔘成分의 抗癌作用과 癌細胞 및 正常細胞內의 NDPase 活性에 對한 硏究 임미재(외)
  53. 中醫免役學 載新民
  54. 上海中醫學雜誌 v.6 健脾中藥防治消化道惡性腫瘤的作用原理硏究 邱佳信(외)
  55. 福建藥物誌 v.一冊;二冊 福建省醫藥硏究會(編)
  56. 中醫腫瘤學(上) 郁仁存
  57. 東國大韓醫大論文集 消積四君子湯, 瓦松 및 鬼箭羽가 MNNG를 投與한 흰쥐의 抗癌作用에 關한 硏3究 尹泰汝
  58. 東洋醫學 v.10 地荊生肝湯의 肝癌治療效果에 關한 硏究 金秉雲
  59. 中醫外科學 顧伯康(외)
  60. 諸病源候論 巢元方
  61. Lab. Invest. v.30 The type 2 cell as progenitor of alveolar epithelial regeneration Adamson, I.Y.R.;Bowden, D.H.
  62. Arch. Pathol. v.90 Oxygen poisoning in mice. Ultrastructural and surfactant studies during exposure and recovery Adamson, I.Y.R.;Bowden, D.H.;Wyatt, J.P.
  63. J. Pathol. v.114 The pathogenesis and structure of paraquat-induced pulmonary fibrosis in rats Smith, P.;Heath, D.;Kay, K.M.
  64. Arch. Pathol. v.99 Pulmonary interstitial fibrosis from paraquat in the hamster Butler, C.
  65. Am. J. Pathol. v.81 Sclerosing alveolitis induced by cyclophosphamide : Ultrastructural observations on alveolar injury and repair Gould, V.E.;Miller, J.
  66. Br. J. Exp. Pathol. v.69 Type 2 pneumocyte responses to cyclosphamide-induced pulmonary injury. Functional and morphological correlation Kumar, P.K.;Truscott, J.Y.;Rhoders, G.C.;Lykke, A.W.J.
  67. Am. J. Pathol. v.77 The pathogenesis of Bleomycin-induced pulmonary fibrosis in mice Adamson, I.Y.R.;Bowden, D.H.
  68. Br. J. Dis. Chest. v.72 Bleomycin lung damage : The pathology and nature of the lesion Jones, A.W.
  69. Lab. Invest. v.35 Morphologic and biochemical study of pulmonary changes induced by Bleomycin in mice Aso, Y.;Yoneda, K.;Kikkawa, Y.
  70. Am. J. Pathol. v.112 Morphometric estimates of infiltrative cellular changes during the development of Bleomycin-induced pulmonary fibrosis in hamsters Chandler, D.B.;Hyde, D.M.;Giri, S.N.
  71. Pulmonary edema. Emphasis on physiologic and toxicological considertions. In mechanisms in respiratory toxicology v.I Cross, C.E.;Parsons, G.H.;Gorin, A.B.;Last, J.A.;Wistshi, H.(ed.);Nettesheim, P.(ed.)
  72. Exp. Lung Res. v.10 Early cellular events in pulmonary fibrosis Reiser, K.M.;Last, L.A.
  73. Exp. Lung Res. v.7 Alterations in alveolar macrophages in hamsters developing pulmonary fibrosis Tryka, A.F.;Godleski, J.J.;Brain, J.D.
  74. Exp. Pathol. v.28 Pulmonary responses to Bleomycin-induced injury. An immunomorphologic and electron microscopic study Kumar, R.K.;Watkins, S.G.;Lykke, A.W.J.
  75. Am. Rev. Respir. Dis. v.119 The effect of antilymphocyte globulin on the development of Bleomycin-induced pulmonary fibrosis in the rat Thrall, R.S.;McCormick, J.R.;Phan, S.H.;Jack, R.H.;Ward, P.A.
  76. Am. Rev. Respir. Dis. v.127 The effects of the nude (nu/nu) mutation on Bleomycin induced pulmonary fibrosis Schrier, D.J.;Phan, S.H.;McGarry
  77. J. Antibictics v.38 Immunological involvement in pulomonarny fibrosis induced by peplomycin Ekimoto, H.;Aikawa, M.;Ohnuki, T.;Takahashi, K.;Matsuda, A.;Takita, T.;Umezawa, H.
  78. Toxicol. Lett. v.26 The effect of cylosporin A on pulmonary fibrosis induced by bytylated hydroxytoluene, Bleomycin and beryllium sulfate Sendelbach, L.E.;Lindenschmidt, R.C.;Witschi, H.P.
  79. Am. Rev. Respir. Dis. v.126 Dif-ferential Cellular analysis of bronchoalveolar lavage fluid obtained at various stages during the development of Bleomycin-induced pulmonary fibrosis in rat Thrall, R.S.;Barton, R.W.;D'Amato, D.A.;Sulavik, S.B.
  80. Toxicol. Pathol. v.14 Analysis of broncho-alveolar lavage fluid from Bleomycin-induced pulmonary fibrosis in hamsters Giri, S.N.;Hyde, D.M.;Nakashima, J.M.
  81. Exp. Lung Res. v.1 Secretion of chemotaxins by guinea pig lung macrophages. I. The spectrum of inflammary cell responses Dauber, J.H.;Daniele, R.P.
  82. Am. Rev. Respir. Dis. v.128 The role of macrophage-derived chemoattractant activities in the early inflammatory events of blemycin-induced pulmonary injury Kaelin, R.M.;Center, D.M.;Bernardo, J.;Grant, M.;Snider, G.L.
  83. Am. J. Pathol. v.84 A macrophage-dependent factor that stimulates the proliferation of fibroblasts in vitro Leibovich, S.J.;Ross, R.
  84. J. Cell. Biol. v.97 Role of fibronectin as a growth factor for fibroblasts Bitterman, P.B.;Rennard, S.I.;Adelberg, S.;Crystal, R.G.
  85. Proc. Natl. Acad. Sci. U.S.A. v.78 Production of fibronectin by the human alveolar macrophages : Mechanism for recruitment of fibroblasts to sites of tissue injury in interstitial lung diseases Rennard, S.I.;Hunninghake, G.W.;Bitterman, P.B.;Crystal, R.G.
  86. J. Clin. Invest. v.70 Human alveolar macrophage growth factor for fibroblast. Regulation and partial characterization Bitterman, P.B.;Rennard, S.I.;Hunninghake, G.W.;Crystal, R.G.
  87. J. Clin. Invest. v.73 Silica-stimulated monocytes release fibroblast proliferation factors identical to interleukin 1. A potential role of interleukin 1 in the pathogenesis of silicosis Schmidt, J.A.;Oliver, C.N.;Lepe-Zuniga, J.L.;Green, I.;Gery, I.
  88. Am. Rev. Respir. Dis. v.131 Human alveolar macrophage inhibition of lung fibroblast growth. A prostaglandin- dependent process Elias, J.A.;Rossman, M.D.;Zurier, R.B.;Daniele, R.P.
  89. Exp. Lung. Res. v.10 Early cellular events in pulmonary fibrosis Reiser, K.M.;Last, J.A.
  90. In immunobiology of the macrophage Lymphocyte-macrophage interactions and macrophage activation in the expression of antimicrobial immunity in vitro Blanden, R.V.;Harpel, A.J.;Doherty, P.C.;Zinkernagel, R.M.;Nelson, D.S.(ed.)
  91. J. Immunol. v.112 Products of activated lymphocytes. Leukocyte inhibitory factor(LIF) distinct from migration inhibitory factor(MIF) Rocklin, R.E.
  92. J. Immunol. v.121 Lymphocyte-mediated activation of fibroblast proliferation and collagen production Wahl, S.M.;Wahl, L.M.;McCarthy, J.B.
  93. Ann. Intern. Med. v.89 The biology and pathology of oxygen radicals McCord, J.M.;Fridovich, I.
  94. Arch. Pathol. Lab. Med v.100 Toxic effects of hydroperoxide injections on rat lung Anderson, W.R.;Tan, W.C.;Takatori, T.;Privett, O.S.
  95. Am. Rev. Respir. Dis. v.130 Neutrophils kill pulmonary endothelial cells by a bydrogenperoxide-dependent pathway. An in vitro model of neutrophil- mediated lung injury Martin, W.J.