한국식품과학회지 (Korean Journal of Food Science and Technology)
- 제31권5호
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- Pages.1363-1370
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- 1999
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- 0367-6293(pISSN)
분자량에 따른 Chitosan의 in vitro 대식세포 활성화
Macrophage Activation of Chitosan Hydrolysates with Different Molecular Weights in vitro
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Chang, Hyun-Joo
(Department of Food and Nutrition, Ewha Womans University) ;
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Chun, Hyang-Sook
(Food Chemistry and Biotechnology Division, Korea Food Research Institute) ;
- Lee, Su-Rae (Department of Food and Nutrition, Ewha Womans University)
- 발행 : 1999.10.31
초록
게껍질 기원의 chitosan을 산가수분해 및 한외여과법으로 제조한 후, 그들의 분자량에 따른 대식세포 활성증진능을 측정하였다. Continuous macrophage cell line J774A.1을 이용한 nitrite 분비능을 비교한 결과, intactchitosan의 농도가
This study was performed to investigate the average molecular weight range of chitosan hydrolysates showing maximum effect in macrophage activation. Nitrite production by continuous macrophage cell line J774A.1 was the highest at