생약학회지 (Korean Journal of Pharmacognosy)
- 제30권4호
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- Pages.377-383
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- 1999
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
인동 추출물의 항천식 효과
Anti-asthmatic Activities of the Extract of Lonicera japonica
- 류근호 (SK케미칼 중앙연구소) ;
- 한창균 (SK케미칼 중앙연구소) ;
- 이해인 (SK케미칼 중앙연구소) ;
- 김택수 (SK케미칼 중앙연구소) ;
- 정인호 (SK케미칼 중앙연구소) ;
- 이성재 (SK케미칼 중앙연구소) ;
- 임광진 (SK케미칼 중앙연구소) ;
- 이강진 (SK케미칼 중앙연구소) ;
- 정기원 (SK케미칼 중앙연구소) ;
- 김대기 (SK케미칼 중앙연구소) ;
- 김기협 (SK케미칼 중앙연구소) ;
- 조용백 (SK케미칼 중앙연구소)
- Ryu, Keun-Ho (Corporate R&D Center, SK Chemicals) ;
- Han, Chang-Kyun (Corporate R&D Center, SK Chemicals) ;
- Rhee, Hae-In (Corporate R&D Center, SK Chemicals) ;
- Kim, Taek-Soo (Corporate R&D Center, SK Chemicals) ;
- Jung, In-Ho (Corporate R&D Center, SK Chemicals) ;
- Lee, Sung-Jae (Corporate R&D Center, SK Chemicals) ;
- Im, Guang-Jin (Corporate R&D Center, SK Chemicals) ;
- Lee, Kang-Jin (Corporate R&D Center, SK Chemicals) ;
- Jeong, Ki-Won (Corporate R&D Center, SK Chemicals) ;
- Kim, Dae-Kee (Corporate R&D Center, SK Chemicals) ;
- Kim, Key-H. (Corporate R&D Center, SK Chemicals) ;
- Cho, Yong-Baik (Corporate R&D Center, SK Chemicals)
- 발행 : 1999.12.30
초록
The anti-asthmatic activities of the extract of Lonicera japonica (BuOH fraction) and its mode of action were investigated using several in vitro and in vivo models. Lonicera japonica was extracted with 30% ethanol (v/v) and successively partitioned into BuOH. The BuOH fraction reduced antigen-induced contraction of isolated trachea from sensitized guinea pigs in a concentration-dependent manner. The BuOH fraction also inhibited histamine release from rat peritoneal mast cells induced by antigen or calcium ionophore A23187 (
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