Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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The Comparative of Inhibitory Effect of Various Solvent Extracts from Aloe arborescens and Aloe vera on Tumor Cell Lines Using Clonoginic Assay

Clonogenic Assay를 이용한 Aloe arborescens와 Aloe vera 용매 추출물의 종양세포 억제효과의 비교

  • Hong, Hee-Sun (The Clinical Research Institute of Catholic Medical Center) ;
  • Lee, Keyong-Ho (Animal Resources Research Center, Konkuk University) ;
  • Kim, Jeong-Hwan (Animal Resources Research Center, Konkuk University) ;
  • Kang, Hee-Gon (Seoul Public Health and Environment Research Institute) ;
  • Cho, Choa-Hyoung (Department of Food Engineering, Iksan National College) ;
  • Kim, Chang-Han (Animal Resources Research Center, Konkuk University)
  • 홍희선 (카톨릭대학교 의과대학 의과학연구원) ;
  • 이경호 (건국대학교 동물자원연구센터) ;
  • 김정환 (건국대학교 동물자원연구센터) ;
  • 강희곤 (서울시 보건환경연구원) ;
  • 조좌형 (국립익산대학 식품공업과) ;
  • 김창한 (건국대학교 동물자원연구센터)
  • Published : 1999.09.30
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Abstract

The solvent extracts from Aloe arborescens and Aloe vera were randomly screened for inhibitory effects on the growth of tumor cell lines. In case of Aloe vera extracts, butyl alcohol extract and ethyl alcohol extract showed antitumor activity at $100\;{\mu}g/ml$ on lung cell lines(A427, Sk-mes-1, Calu-3 and 3LL). In Aloe arborescens extracts, butyl alcohol extract and ethyl alcohol extract exerted high activity at $100\;{\mu}g/ml$ on breast cell line(Hs-578T) and lung cell line(Sk-mes-1), respectively. The solvent extracts from Aloe vera exerted antitumor activity broadly on various tumor cell lines. In contract, the solvent extracts from Aloe arborescens exerted specific antitumoricity on a few tumor cell lines.

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