Isolation of a Potent Mosquito Repellent from Vitex negundo L.: An Alternative Source of Rotundial

  • Amancharla, Praveen K. (Research and Development Centre, E. I. D. Parry (India) Ltd.) ;
  • Muthuraj, Patrick S. (Research and Development Centre, E. I. D. Parry (India) Ltd.) ;
  • Rao, Gottumukkala V. (Research and Development Centre, E. I. D. Parry (India) Ltd.) ;
  • Singh, Om V. (Research and Development Centre, E. I. D. Parry (India) Ltd.)
  • Published : 1999.06.01

Abstract

The chloroform fraction of the aqueous extract of the fresh leaves of Vitex negundo by bioactivity guided isolation yielded a pure compound, rotundial (1) which has shown potent mosquito repellent activity. Using spectral data (UV, IR, $^1H\;&\;^{13}C$ NMR and MS) its structure has been elucidated.

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