생물정신의학 (Korean Journal of Biological Psychiatry)
- 제5권2호
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- Pages.162-165
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- 1998
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- 1225-8709(pISSN)
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- 2005-7571(eISSN)
강박장애의 약물효과 증대 전략
Augmentation Strategies in Obsessive Compulsive Disorder
초록
The serotonin reuptake inhibitors(SRIs) and the serotonin selective reuptake inhibitors(SSRIs) are considered the first choice agents for pharmacologic treatment of obsessive-compulsive disordr(OCD). However, many patients with OCD experience little or no improvement in their symptoms when treated with SRIs or SSRIs. Patients who have experienced a partial or no response to an SRI/SSRI at 10 to 12 weeks are often considered for augmentation strategies. Nearly every class of psychotropic medications has been tried in an open fashion, though augmentation strategies have been somewhat disappointing.