BMB Reports
- Volume 31 Issue 6
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- Pages.604-606
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- 1998
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- 1976-670X(eISSN)
Characteristics of Hypervariable Regions of Mitochondrial DNA in Korean Population
- Han, Jae-Seok (Department of Molecular Biology and Research Center for Cell Differentiation, Seoul National University) ;
- Lee, Dong-Hoon (Department of Molecular Biology and Research Center for Cell Differentiation, Seoul National University) ;
- Rho, Hyune-Mo (Department of Molecular Biology and Research Center for Cell Differentiation, Seoul National University)
- Received : 1998.07.13
- Accepted : 1998.08.12
- Published : 1998.11.30
Abstract
The nucleotide sequence of two hypervariable regions of the D-loop and the frequency of the 9-bp repeat in the region V of mitochondrial DNA (mtDNA) were investigated in the Korean population. Alignment of these sequences with the published reference revealed a unique pattern of base substitution and deletion compared with those of other races. The deletion and addition frequency of the 9-bp repeat in the region V was also distinct.