Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Diffuse Pulmonary Infiltration Rapidly Progressed after the Chemotherapy of a Patient with Malignant Lymphoma

악성 임파종의 항암 치료 후 빠르게 진행되는 범발성 폐침윤

  • Sohn, Jang-Won (Department of Internal Medicine, College of Medicine, Hanyang University) ;
  • Shin, Dong-Ho (Department of Internal Medicine, College of Medicine, Hanyang University) ;
  • Yang, Seok-Chul (Department of Internal Medicine, College of Medicine, Hanyang University) ;
  • Yoon, Ho-Joo (Department of Internal Medicine, College of Medicine, Hanyang University) ;
  • Park, Sung-Soo (Department of Internal Medicine, College of Medicine, Hanyang University) ;
  • Lee, Jung-Hee (Department of Internal Medicine, College of Medicine, Hanyang University) ;
  • Lee, Young-Yul (Department of Internal Medicine, College of Medicine, Hanyang University) ;
  • Choi, Yo-Won (Department of Radiology, College of Medicine, Hanyang University) ;
  • Park, Moom-Hyang (Department of Pathology, College of Medicine, Hanyang University)
  • 손장원 (한양대학교 의과대학 내과학교실) ;
  • 신동호 (한양대학교 의과대학 내과학교실) ;
  • 양석철 (한양대학교 의과대학 내과학교실) ;
  • 윤호주 (한양대학교 의과대학 내과학교실) ;
  • 박성수 (한양대학교 의과대학 내과학교실) ;
  • 이정희 (한양대학교 의과대학 내과학교실) ;
  • 이영열 (한양대학교 의과대학 내과학교실) ;
  • 최요원 (한양대학교 의과대학 진단 방사선학교실) ;
  • 박문향 (한양대학교 의과대학 병리학교실)
  • Published : 1998.04.30
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Abstract

Acute respiratory failure with diffuse pulmonary infiltration was occurred in a patient with malignant lymphoma 1month after the $8^{th}$ CHOP chemotherapy. The ground glass and consolidation appearances on chest C-T in this immunodeficient patient could be presented in many clinical situations such as pneumonia by opportunistic infections (fungal, parasites, viral, and usual bacterial pathogens), anti-tumor drug's pulmonary toxicity and tumor invasion. And the other diseases of acute interstitial pneumonitis, alveolar proteinosis, BOOP, puhnonary edema and alveolar hemorrhage, which could present the same radiological findings, should included in differential diagnosis. This patient was diagnosed as the opportunistic pneumonia by Pneumocystis carinii and probably Cytomegalovirus through bronchoalveolar lavage and transbronchial lung biopsy

저자들은 악성 임파종의 항암요법후 갑자기 진행되는 폐침윤(ground glass & consolidation) 소견을 보인 Pneumocystis carinii(PCP)와 Cytomegalovirus(CMV)의 복합 폐염 환자를 치료하였으나 계속 진행되는 호흡 부전으로 사망하였다.

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