Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
권호 표지

A Case of Invasive Pulmonary Aspergillosis in an Immunocompetent Host

정상 면역가능을 가진 환자에서 발생한 침습성 폐진균증 1예

  • Lim, Young-Hee (Sung Kyun Kwan University, College of Medicine, Samsung Medical Center, Department of Internal Medicine, Division of pulmonology) ;
  • Cheon, Eun-Mee (Sung Kyun Kwan University, College of Medicine, Samsung Medical Center, Department of Internal Medicine, Division of pulmonology) ;
  • Kim, Ho-Cheol (Sung Kyun Kwan University, College of Medicine, Samsung Medical Center, Department of Internal Medicine, Division of pulmonology) ;
  • Suh, Gee-Young (Sung Kyun Kwan University, College of Medicine, Samsung Medical Center, Department of Internal Medicine, Division of pulmonology) ;
  • Park, Jeong-Woong (Sung Kyun Kwan University, College of Medicine, Samsung Medical Center, Department of Internal Medicine, Division of pulmonology) ;
  • Kwon, O-Jung (Sung Kyun Kwan University, College of Medicine, Samsung Medical Center, Department of Internal Medicine, Division of pulmonology) ;
  • Rhee, Chong-H. (Sung Kyun Kwan University, College of Medicine, Samsung Medical Center, Department of Internal Medicine, Division of pulmonology) ;
  • Lee, Jae-Young (Sung Kyun Kwan University, College of Medicine, Samsung Medical Center, Department of Internal Medicine, Division of Diagnostic Radiology) ;
  • Lee, Kyung-Soo (Sung Kyun Kwan University, College of Medicine, Samsung Medical Center, Department of Internal Medicine, Division of Diagnostic Radiology) ;
  • Han, Jeong-Ho (Sung Kyun Kwan University, College of Medicine, Samsung Medical Center, Department of Internal Medicine, Division of Diagnostic Pathology)
  • 임영희 (성균관대학교 의과대학 삼성서울병원 호흡기내과) ;
  • 천은미 (성균관대학교 의과대학 삼성서울병원 호흡기내과) ;
  • 김호철 (성균관대학교 의과대학 삼성서울병원 호흡기내과) ;
  • 서지영 (성균관대학교 의과대학 삼성서울병원 호흡기내과) ;
  • 박정웅 (성균관대학교 의과대학 삼성서울병원 호흡기내과) ;
  • 권오정 (성균관대학교 의과대학 삼성서울병원 호흡기내과) ;
  • 이종헌 (성균관대학교 의과대학 삼성서울병원 호흡기내과) ;
  • 이재영 (성균관대학교 의과대학 삼성서울병원 영상의학과) ;
  • 이경수 (성균관대학교 의과대학 삼성서울병원 영상의학과) ;
  • 한정호 (성균관대학교 의과대학 삼성서울병원 진단병리과)
  • Published : 1998.02.28
Download PDF
⟨ Previous Next ⟩

Abstract

Invasive pulmonary aspergillosis is a disease occuring predominantly in patients with defects in immunity such as neutropenia, hematologic malignancies or with defects in cell-mediated immunity. The isolation of Aspergillus from respiratory tract of normal host usually signifies tracheobronchial colonization, making this diagnosis difficult. There are isolated case reports occuring in normal hosts but most of them were diagnosed postmortem at autopsies indicating that early diagnosis of invasive aspergillosis in normal host is difficult. We describe here a case of invasive aspergillosis in a immunocompetent host diagnosed by lung biopsy which was successfully treated with Amphotericin-B. Invasive pulmonary aspergillosis should be included as one of the differential diagnosis if a patient with pneumonic consolidation does not respond to usual therapy, even if the patient does not have any defect in immunity.

Keywords