대한두경부종양학회지 (Korean Journal of Head & Neck Oncology)
- 제14권2호
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- Pages.199-205
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- 1998
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- 1229-5183(pISSN)
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- 2586-2553(eISSN)
갑상선 결절의 Telomerase 활성도에 대한 분석
Telomerase Activity in Benign and Malignant Thyroid Diseases
- Park Cheong-Soo (Department of Surgery, Yonsei University College of Medicine) ;
- Chung Woong-Youn (Department of Surgery, Yonsei University College of Medicine) ;
- Lee Mi-Kyung (Department of Pathology, Yonsei University College of Medicine) ;
- Chang Hang-Suk (Department of Surgery, Yonsei University College of Medicine)
- 발행 : 1998.11.01
초록
Objective: Telomerase, a specialized ribonucleoprotein polymerase associated with cellular immortality, is expressed by most malignant cells and is inactive in most normal somatic cells. The assays of telomerase activity in various tumors have provided both diagnostic and prognostic information. This study was carried out to determine whether telomerase activity could be useful in distinguishing benign and malignant thyroid diseasees. Materials & Methods: Telomerase activity was determined using Oncor