Journal of Korean Academy of Oral and Maxillofacial Radiology (치과방사선)

Korean Academy of Oral and Maxillofacial Radiology (대한영상치의학회)
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FAILURE OF ODONTOGENESIS AFTER CHEMO-RADIATION THERAPY FOR RHABDOMYOSARCOMA

횡문근육종의 항암제-방사선치료 후 치아발육장애

  • Choi Sun-Young (Department of Oral and Maxillofacial Radiology, School of Dentistry, Chonbuk National University) ;
  • Hong Sung-Woo (Department of Oral and Maxillofacial Radiology, School of Dentistry, Chonbuk National University) ;
  • Koh Kwang-Joon (Department of Oral and Maxillofacial Radiology, School of Dentistry, Chonbuk National University)
  • 최선영 (전북대학교 치과대학 구강악안면방사선학교실) ;
  • 홍성우 (전북대학교 치과대학 구강악안면방사선학교실) ;
  • 고광준 (전북대학교 치과대학 구강악안면방사선학교실)
  • Published : 1998.02.01
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Abstract

This report details a case of 8-year-old girl showing failure of odontogenesis after chemo-radiation therapy for the rhabdomyosarcoma at the age of 4. The observed results were as follows : 1. Past history revealed that she had received for a total radiation dose of 4430cGy, 29 fractions in 6 weeks and chemotherapy with vincristine, actinomycin D and cytoxan, followed as maintenance phase for 2 years. 2. The patient was symptom -free and appointed for the treatment of multiple dental caries. 3. Oral examination showed hypoplastic enamel on whole erupted permanent teeth and showed retarded eruption. 4. Conventional radiograms showed failure of root development including abrupt cessation of root formation and root agenesis, and microdontia, missing teeth, irregular enamel, dislocation of the impacted teeth. Additional finding showed good healing bone pattern on the left mandibular ramus and angle area. 5. Cephalometric analysis revealed failure of bite raising due to incomplete eruption of all the first molars and made it possible to suspect entrapped mandibular growth and then Class II tendency growth. 6. There was correlation between the time of chemo-radiation therapy and the damage of the teeth.

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