Archives of Pharmacal Research
- Volume 21 Issue 6
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- Pages.744-748
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- 1998
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Synthesis of Praziquantel Derivatives and Their In Vitro Activity Against Adult Clonorchis sinensis
- Kim, Choong-Sup (Division of Applid Science, Korea Institute of Science & Technology) ;
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Min, Duk-Young
(Department of Parasitology, College of Medicine, Hanyang University)
- Published : 1998.12.01
Abstract
Several praziquantel derivatives have been prepared by the acylation of compound 5, and examined on their biological activity in vitro agninst adult clonorchis sinensis collected from rabbits infected with metacercariae which was isolated from Pseudorasbora parva, a second intermediate host, captured in Nakdong river in Korea.