The Journal of Korean Society of Virology (대한바이러스학회지)

The Korean Society of Virology (대한바이러스학회)
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Serological Study on Hantavirus Infection of Wild Rodents Captured in the Mountains of Kangwon Province in Korea

강원도 산악지대에서 채집한 야생들쥐의 한타바이러스 감염에 대한 혈청학적 연구

  • Baek, L.J. (Department of Microbiology, The Institute for Viral Diseases, College of Medicine, Korea University) ;
  • Song, K.J. (Department of Microbiology, The Institute for Viral Diseases, College of Medicine, Korea University) ;
  • Song, J.W. (Department of Microbiology, The Institute for Viral Diseases, College of Medicine, Korea University) ;
  • Chung, K.M. (Department of Microbiology, The Institute for Viral Diseases, College of Medicine, Korea University) ;
  • Kho, E.Y. (Department of Microbiology, The Institute for Viral Diseases, College of Medicine, Korea University) ;
  • Park, K.S. (Department of Microbiology, The Institute for Viral Diseases, College of Medicine, Korea University) ;
  • Lee, Y.J. (Department of Microbiology, The Institute for Viral Diseases, College of Medicine, Korea University)
  • 백락주 (고려대학교 의과대학 미생물학교실, 바이러스병연구소) ;
  • 송기준 (고려대학교 의과대학 미생물학교실, 바이러스병연구소) ;
  • 송진원 (고려대학교 의과대학 미생물학교실, 바이러스병연구소) ;
  • 정기모 (고려대학교 의과대학 미생물학교실, 바이러스병연구소) ;
  • 고은영 (고려대학교 의과대학 미생물학교실, 바이러스병연구소) ;
  • 박광숙 (고려대학교 의과대학 미생물학교실, 바이러스병연구소) ;
  • 이용주 (고려대학교 의과대학 미생물학교실, 바이러스병연구소)
  • Published : 1998.09.30
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Abstract

Hantaan virus are widely distributed in rodents populations in Korea. Two antigenically distinct hantaviruses have been isolated from Apodemus agrarius in 1976 and Rattus norvegicus in 1980 in Korea. This study was designed to find the serological evidence of hantavirus infection among indigenous wild rodents captured in 7 Mountains located in Kangwon province of south Korea. A total 191 wild rodents of 3 species were trapped in Chumbong mountain, Kali mountain, Hansuk mounatin, Chachil peak, Bukam ridge, Kyebang mountain and Odae mountain in 1997. Serologic evidence for hantavirus infection were tested using hantavirus antigens by indirect immunofluorescent antibody technique (IFA). Among 85 Apodemus agrarius, 77 Apodemus peninsulae and 29 Eothenomys regulus; 8 A. agrarius (9.4%), 11 A. peninsulae (14.3%) and 4 E. regulus (13.8%) were immunofluorescent antibody positive against hantaan virus. IF antibody titers against Puumala virus of 3 E. regulus sera were higher than against hantaan virus. This data suggest that several antigenically distinct hantaviruses have been circulated in rodent populations in Korea.

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