Toxicological Research
- 제14권4호
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- Pages.563-567
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- 1998
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- 1976-8257(pISSN)
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- 2234-2753(eISSN)
고성능 역상 액체 크로마토그래피를 이용한 넙치에서의 Josamycin의 약물동태에 관한 연구
The Pharmacokinetic Study of Josamycin in Flounder by Reversed Phase High Performance Liquid Chromatography
초록
This study was conducted to observe the distribution of josamycin, a macrolide antibiotic in flounder. Josamycin was administered orally to the flounder at the dose of 100 mg 1 kg josamycin in flounder. Josamycin in blood and various organs of flounder was analyzed using reversed phase HPLC. In blood kinetics study, Cmax was shown 9.50