Toxicological Research
- Volume 14 Issue 4
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- Pages.563-567
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- 1998
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- 1976-8257(pISSN)
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- 2234-2753(eISSN)
The Pharmacokinetic Study of Josamycin in Flounder by Reversed Phase High Performance Liquid Chromatography
고성능 역상 액체 크로마토그래피를 이용한 넙치에서의 Josamycin의 약물동태에 관한 연구
Abstract
This study was conducted to observe the distribution of josamycin, a macrolide antibiotic in flounder. Josamycin was administered orally to the flounder at the dose of 100 mg 1 kg josamycin in flounder. Josamycin in blood and various organs of flounder was analyzed using reversed phase HPLC. In blood kinetics study, Cmax was shown 9.50