Journal of Microbiology and Biotechnology
- Volume 8 Issue 4
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- Pages.406-408
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- 1998
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- 1017-7825(pISSN)
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- 1738-8872(eISSN)
Cytotoxic Ophiobolins Produced by Bipolaris sp.
- Ahn, Jong-Woong (Korea Research Institute of Chemical Technology) ;
- Lee, Mi-Kyoung (Korea Research Institute of Chemical Technology) ;
- Choi, Sang-Un (Korea Research Institute of Chemical Technology) ;
- Lee, Chong-Ock (Korea Research Institute of Chemical Technology) ;
- Kim, Byung-Sup (Department of Horticulture, Kangnung National University)
- Published : 1998.08.01
Abstract
6-Epiophiobolin A, 3-anhydro-6-epiophiobolin A, and ophiobolin I were isolated from culture broth of Bipolaris sp. as cytotoxic agents against human tumor cells. Both 6-epiophiobolin A and 3-anhydro derivatives demonstrated significant cytotoxicity, having